CONSIDERATIONS TO KNOW ABOUT METHADONE USE ICD 10 CODE

CYP2B6 is The main CYP enzyme associated with the metabolism of S-methadone and also to an extent, R-methadone. The expression of CYP2B6Opioids (Blended Agonist / Antagonist): May possibly diminish the analgesic effect of Opioid Agonists. Management: Search for alternatives to mixed agonist/antagonist opioids in patients getting pure opioid agonist